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--- thelancet com journals langlo article PIIS2214-109X(21)00572-6 fulltexttheconversation com benefits-of-statins-may-have-been-overstated-new-stud --- euractiv com section uk-and-us-at-odds-with-europe-over-statin-use--- sciencedirect com science article pii S0021915021002525--- ahajournals org doi pdf 10 1161 CIRCOUTCOMES 117 003811In Denmark, statin therapy has increased tremendously over the past 20 years with great variability in the proportionate use of different types of statins Somewhat surprisingly, total statin expenditure has dropped since 2002 as a consequence of decreasing statin costs per DDD and is now below that in 1998 --- ncbi nlm nih gov pmc articles PMC9462115--- theguardian com society 2023 jan new-statins-guidelines-nice-nhs-englandObjective Prior studies have reported inequitable global access to essential medicines for cardiovascular disease (CVD) prevention, especially statins Here we examine recent trends and disparities in statin utilisation at the income group, regional and country levels Design Ecological study Pharmaceutical sales data were used to examine statin utilisation in high-income counties (HICs) and According to the study, statins would reduce the relative risk of dying by 9% In absolute terms, the man would reduce his risk from 38% to 34 6%, and the woman from 1 4% to 1 3% Patients and Furthermore, with the low cost of generic statins, this strategy is likely to be cost effective Although we are not recommending the use of statins for all patients to achieve a reduction in cardiovascular burden, statin therapy should be considered for all patients with established atherosclerotic cardiovascular disease or those at a high risk of developing the condition First published on Thu 12 Jan 2023 07 20 EST As many as 15 million more people could be eligible for cholesterol-lowering statins to protect them against heart attacks and strokes, according to Highlights • From 2008 to 2018, global use of lipid-modifying agents (LMAs) increased at an annual compound rate of 4 13% • Statins are the most used and fibrates are the second most used class of LMAs • An estimated 173 million people, or 3 1% of the included countries' inhabitants, used an LMA daily in 2018 • Statins are already the United Kingdom’s most commonly prescribed medicines – roughly 6 million Brits take the drugs on a regular basis to lower the risk of a cardiovascular incident, in line The ACC AHA guidelines were shown to potentially lead to higher rates of statin recommendations than the ESC EAS guidelines in 2 low-risk Western European cohorts owing to higher numbers of adults meeting the CVD risk thresholds for primary prevention 5,6 Nevertheless, the population-wide implications of the ACC AHA and ESC EAS guidelines remain unclear given other differences between the 2 jamanetwork com journals jamacardiology fullarticle 2532057Results showed that although the new 2021 European guidelines introduced a new and improved risk model, known as SCORE2, the updated age-specific recommendations dramatically reduced eligibility --- medscape com viewarticle 976715Introduction Cardiovascular disease (CVD)—primarily ischaemic heart disease (IHD)—causes approximately one-third of deaths worldwide 1 While age-standardised CVD mortality rates have declined globally, the number of deaths due to CVD has increased from 12 1 million in 1990 to 18 6 million in 2019, 1 and substantial regional, income group and country-level disparities exist 2 3 For bmjopen bmj com content 12 9 e061350
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